UNIQUE PRODUCTS, BACKED BY REAL SCIENCE
By utilizing and employing researchers, medical doctors, registered dieticians, and other industry experts to focus solely on the discovery and development of patented and patentable products that are new and exclusive to the marketplace, BioGenetic Laboratories is able to focus on providing legitimate, scientific evidence to its product claims. All of our product claims are derived through independent clinical trial research study evaluations of our Scientific Medical Advisory Board. BioGenetic Laboratories places a high value on you, the educated consumer. We know you are the type of consumer who understands and values the scientific evidence that accompany our supplements and is likely to give them a try based on the trust we have earned from the millions of customers we have successfully served over the past 10 years. And, when you achieve your intended result, you’re likely to purchase them again and perhaps try another BioGenetic offering. We call this a relationship—based on trust—and we hope to earn yours through providing real science, unique products, and delivering unreal results.

SCIENTIFIC REFERENCES AND STUDY SUMMARIES ON

GARCINIA TRIM™

Emotional Eaters May Benefit from the power of Hydroxy Citric Acid

A recent study, featured on America’s most trusted doctor's television show, featured the use of hydroxycitric acid (HCA) extract from Garcinia cambogia with 60 obese people , who were placed on a calorie-reduced diet combined with HCA for eight weeks, and lost an average of 14 pounds (compared to 6.1 pounds in the placebo group). Participants in the study reported no side effects. Other research has indicated that even with no changes to diet or exercise, weight loss is still experienced.

This study quickly got the attention of the media and America’s most trusted doctor
Garcinia cambiogia fruit naturally contain a powerful compound called Hydroxycitric Acid (HCA) which is the active weight-loss compound found in Garcinia Trim.

Scientific Summary on Hydroxycitric Acid Studies
In another recent study published in the Diabetes, Obesity, and Metabolism journal, scientists used Garcinia cambogia with 60% (GCA®) to study its weight loss effects. What they found was nothing short of remarkable. It caused significant weight loss, reduces emotional urges to eat, as well as promoting health factors such as lower cholesterol (LDL), low-density lipoproteins, triglycerides, and serum leptin levels. You can see the full clinical study by Clicking here.

Garcinia cambogia with 60% Hydroxycitri Acid (GCA®)
It's important to note that it was ONLY Garcinia cambogia that contained 60% Hydroxycitric Acid (GCA®) used in the study, which is what is found in Garcinia Trim™. Not a cheaper imported extract. Garcinia Trim™, from BioGenetic Laboratories, contains 60% Hydroxycitric Acid (GCA®), as verified by independent laboratory analysis, which is the key to weight loss in Garcinia cambogia, while other products likely contain much lower contents, between 30-50%.

  1. Igho Onakpoya, Shao Kang Hung, Rachel Perry, Barbara Wider, and Edzard Ernst, “The use of Garcinia Extract (Hydroxycitric Acid) as a weight loss supplement: A Systematic Review and Meta-Analysis of Randomised Clinical Trials”. Journal of Obesity, Volume 2011 (2011), Article ID 509038, doi:10.1155/2011/509038.

hCG ALTERNATIVE™

hCG ALTERNATIVE™, the weight-loss breakthrough that compliments America’s most popular low calorie diet”

hCG ALTERNATIVE contains absolutely no hCG drug, no hormones, and it is a natural combination of ingredients that serve as a healthy alternative to hormone administration. hCG ALTERNATIVE does not claim to be a "miracle pill" but instead uses an exclusive dietary formula combined with a progressive diet plan to help you reach your goals faster.

hCG stands for human chorionic gonadotropin (pronounced Core-eon-ik Go-na-do-tro-pin). It is a hormone produced naturally by men and women (and substantially higher while a woman is pregnant). It is normally administered by a medical doctor in daily, painful injections that cost about $400 to $600 per month. When used in conjunction with a low calorie, balanced macronutrient-based diet, it may help your body exert and use more stored energy.

Scientific Summary on Studies of the Key Ingredients in hCG ALTERNATIVE
There are numerous clinical studies documenting the healthy, weight-loss and psychological effects of the key ingredients inside hCG ALTERNATIVE. These studies are listed below in the “Additional Supporting Research” section. And, equally important, these studies reported the ingredients were safe to use.

Natural “Appetite-Control” from Saffron Extract
The exciting news is a natural appetite regulator, a natural plant extract, has been identified that operates at the neurochemical level to help provoke “satiety”—the feeling of being full. This unique extract is derived from saffron, prized for centuries not only as a spice but also as a mood enhancer in traditional cultures.

In one of the most compelling findings on emotional eating, Dutch researchers reported that compulsive eating can result from a common gene variant for the molecule that transports serotonin, one of the body’s primary “mood regulators.” People carrying this gene suffer from lower serotonin activity, predisposing them to depression and anxiety, especially under stress. In fact, the Dutch study revealed that teens carrying this gene indulge in emotional eating at a significantly higher rate.

More interesting to Bourges and his team of researchers were the significant declines in reported feelings of hunger between meals, an effect that persisted until dinner in 25% of women taking the saffron extract. In contrast, 50% of placebo recipients reported an increased desire to eat. By the end of the study, 100% of women in the saffron group reported successful reduction in daily between-meal eating, as opposed to controls, who saw no improvement.

With these impressive findings, Bourges and his team launched a full-scale clinical trial of 60 slightly overweight women 25 – 45 years old. This time, they focused specifically on women who reported frequent, anxiety-related between-meal and after-dinner snacking. Their goal was to test the saffron’s psychotropic (“mood-altering”) potential in helping to reduce the anxiety behind compulsive eating.
Once again, weight loss was relatively modest: over one pound at the two-week mark versus a slight gain in the placebo group. By eight weeks, the average weight loss had increased, reaching just over two pounds, with 26% of subjects losing up to 11 pounds. Interestingly, women taking saffron saw a significant reduction in thigh circumference.

It was the psychological effect reported in the saffron group that again proved most compelling, especially given the susceptibility to compulsive between-meal consumption. The women reported a significant reduction in feelings of hunger before meals. They also experienced a significantly diminished “need” to snack between meals. The favorable alteration in these urges had tangible results. At baseline, women in both groups had reported an average of about 12 snacking episodes per week. After eight weeks, the average was just six episodes per week in the saffron group—a 50% reduction.

These results validated the French team’s hypothesis: something about this particular saffron extract was working to control the compulsion to eat in this vulnerable sample of women. They reported that “subjects in the saffron group felt significantly more alert and energetic than the placebo group”—feelings that correspond with emergence from sub-clinical depression and anxiety. As noted above, depression and anxiety are the foundation for compulsive eating.

Supports Healthy Body Mass and Composition
America’s looming overweight epidemic has encouraged scientists to seek new agents that promote healthy body weight and composition. Certain spicy foods and herbal drinks have long been used as weight-management tools because of their purported ability to promote thermogenesis or satiety.

During the past decade, green tea has received particular attention for its role in promoting healthy weight management. Its weight-control effects have been studied extensively in cell, animal, and human studies. In all, there have been over 1,500 published studies in the last five years alone. Laboratory and animal models suggest that green tea, green tea polyphenols known as catechins, and green tea’s principal catechin, EGCG, may work to promote healthy weight management by:

  • reducing fat cell proliferation
  • decreasing body and fat mass
  • inhibiting fat absorption
  • lowering blood levels of triglycerides, cholesterol, glucose, and insulin.

At the same time, green tea has been found to increase the oxidation (breakdown) of fats. Human studies suggest that green tea consumption is associated with decreased body mass and body fat.

  • Wolfram S, Wang Y, Thielecke F. Anti-obesity effects of green tea: from bedside to bench. Mol Nutr Food Res. 2006 Feb;50(2):176-87.
  • Dulloo AG, Seydoux J, Girardier L, Chantre P, Vandermander J. Green tea and thermogenesis: interactions between catechin-polyphenols, caffeine and sympathetic activity. Int J Obes Relat Metab Disord. 2000 Feb;24(2):252-8.
  • Shixian Q, Vancrey B, Shi J, Kakuda Y, Jiang Y. Green tea extract thermogenesis-induced weight loss by epigallocatechin gallate inhibition of catechol-o-methyltransferase. J Med Food. 2006;9(4):451-8.
  • Juhel C, Armand M, Pafumi Y, et al. Green tea extract (AR25) inhibits lipolysis of triglycerides in gastric and duodenal medium in vitro. J Nutr Biochem. 2000 Jan;11(1):45-51.
    Hsu TF, Kusumoto A, Abe K, et al. Polyphenol-enriched oolong tea increases fecal lipid excretion. Eur J Clin Nutr. 2006 Nov;60(11):1330-6.
  • Klaus S, Pultz S, Thone-Reineke C, Wolfram S. Epigallocatechin gallate attenuates diet-induced obesity in mice by decreasing energy absorption and increasing fat oxidation. Int J Obes (Lond). 2005 Jun;29(6):615-23.
  • High Bioavailability of a Standardized Green Tea Extract. NUTRAfoods 7(4) 21-28 (2008).
    Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans. Am J Clin Nutr 1999; 70: 1040-5.
  • Anti-obesity effects of green tea: from bedside to bench. Mol Nutr Food Res. 2006 Feb; 50(2):176-87.

Additional Supporting Research for green tea (Camellia sinesis) in particular to health benefits:

  • Belza A, Toubro S, Astrup A. The effect of caffeine, green tea and tyrosine on thermogenesis and energy intake. Eur J Clin Nutr. 2007; [Epub ahead of print].
  • Boschmann M, Thielecke F. The effects of epigallocatechin-3-gallate on thermogenesis and fat oxidation in obese men: a pilot study. J Am Coll Nutr. 2007;26(4):389S-395S.
  • Brown AL, Lane J, Holyoak C, Nicol B, Mayes AE, Dadd T. Health effects of green tea catechins in overweight and obese men: a randomised controlled cross-over trial. Br J Nutr. 2011 Jun 7:1-10. [Epub ahead of print]
  • Diepvens K, Westerterp KR, Westerterp-Plantenga MS. Obesity and thermogenesis related to the consumption of caffeine, ephedrine, capsaicin and green tea. Am J Physiol Regul Integr Comp Physiol. 2007;292(1):R77-85.
  • Fujita H, Yamagami T. Antihypercholesterolemic effect of Chinese black tea extract in human subjects with borderline hypercholesterolemia. Nutr Res. 2008;28(7):450-6.
  • Fukino Y, Ikeda A, Maruyama K, Aoki N, Okubo T, Iso H. Randomized controlled trial for an effect of green tea-extract powder supplementation on glucose abnormalities. Eur J Clin Nutr. 2007; [Epub ahead of print].
  • Hsu CH, Liao YL, Lin SC, Tsai TH, Huang CJ, Chou P. Does supplementation with green tea extract improve insulin resistance in obese type 2 diabetics? A randomized, double-blind, and placebo-controlled clinical trial. Altern Med Rev. 2011 Jun;16(2):157-63.
  • Jin X, Zheng RH, Li YM. Green tea consumption and liver disease: a systematic review. Liver Int. 2008;28(7):990-6.
  • Katiyar SK, Ahmad N, Mukhtar H. Green tea and skin. Arch Dermatol. 2000;136(8):989-94.
  • Kimura K, Ozeki M, Juneja LR, Ohira H. L-Theanine reduces psychological and physiological stress responses. Biol Psychol. 2007;74(1):39-45.
  • Koo SI, Noh SK. Green tea as inhibitor of the intestinal absorption of lipids: potential mechanism for its lipid-lowering effect. J Nutr Biochem. 2007;18(3):179-83.
  • Kovacs EM, Lejeune MP, Nijs I, Westerterp-Plantenga MS. Effects of green tea on weight maintenance after body-weight loss. Br J Nutr Mar 1, 2004;91(3):431-437.
  • Lee W, Min WK, Chun S, Lee YW, Park H, Lee do H, Lee YK, Son JE. Long-term effects of green tea ingestion on atherosclerotic biological markers in smokers. Clin Biochem. Jan 1, 2005;38(1):84-87.
  • McKenna DJ, Hughes K, Jones K. Green tea monograph. Alt Ther. 2000;6(3):61-84.
  • Miura Y, Chiba T, Tomita I, et al. Tea catechins prevent the development of atherosclerosis in apoprotein E-deficient mice. J Nutr. 2001;131(1):27-32.
  • Nagao T, Hase T, Tokimitsu I. A green tea extract high in catechins reduces body fat and cardiovascular risks in humans. Obesity (Silver Spring). 2007;15(6):1473-83.
  • Peters U, Poole C, Arab L. Does tea affect cardiovascular disease? A meta-analysis. Am J Epidemiol. 2001;154(6):495-503.
  • Ryu OH, Lee J, Lee KW, et al. Effects of green tea consumption on inflammation, insulin resistance and pulse wave velocity in type 2 diabetes patients. Diabetes Res Clin Pract. 2006;71(3):356-8.
  • Thavanesan N. The putative effects of green tea on body fat: an evaluation of the evidence and a review of the potential mechanisms. Br J Nutr. 2011 Aug 3:1-13. [Epub ahead of print]
  • Westerterp-Plantenga MS, Lejeune MP, Kovacs EM. Body weight and weight maintenance in relation to habitual caffeine intake and green tea. Obes Res Jul 2005;13(7):1195-1204.

BioGenetic Laboratories engineers weight-loss breakthrough products to help you achieve your weight-loss goals and ultimately help you feel lighter, healthier, and more confident. You have our promise to be there every step of the way during your weight-loss journey. So if you're searching for a premium, science-based company that provides top-notch support and caring success coaches to help you reach your goals, look no further than Biogenetic Laboratories and our line of top-quality products, designed by the foremost researchers and nutrition doctors to help you live a healthier, happier life.

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